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Delivering drug discovery via our unique display technology

Peptide
Discovery

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Peptide Display
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What we do

Orbit Discovery offer services for the discovery of peptides and other small biologic based moieties. Our services address high throughput screening of chemical space and allow for affinity screening and functional screening using both bead based technologies and microfuidics.

These technologies have been used to identify peptides as the starting point for peptidomimetic and small molecule therapeutics ,as well as bioconjugates for cell targeting and cargo delivery. Furthermore, the functional screening capabilities has allowed us to build screening cascades for the direct identification of functional peptides, in particular against GPCR’s.

Orbits mission is to offer our Partners solutions to identify therapeutic candidates by adopting high throughput affinity and functional screening.

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Affinity Screening Service

A bead based peptide display engine, using FACS, allows for faster peptide discovery by binding affinity.

Functional Screening Service

The ability to display high peptide copy number allows discovery of functional peptides, such as agonists and antagonists, in primary screens

Target Production Services

The Orbit platform is target agnostic giving access to cell surface receptors, notably GPCRs and ion channels. We have a dedicated team focused on production of targets to ensure quality of starting materials

Single Cell Reporter Assay Services

Using expertise in cell line development and assay development, in conjunction with FACS, high content imaging and microfluidics, the Orbit platform can distinguish a functional response from single cells

Establishing a new standard

Orbit works with both industry and academic Partners to identify hits for existing and novel drug targets where therapeutic peptides can establish a new standard of care.  

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Find out how Orbit can help you with peptide discovery

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