Lydia Aschauer is the senior research scientist responsible for establishing cell models for the cellular functional screening at Orbit Discovery. She has about ten years research experience mostly acquired in an academic background.
Previously, she was a Postdoc at the MRC Toxicology in Leicester investigating the effect of metals on the tumour-suppressor p53. Her research showed that metals induce a conformational change in p53 resulting in tumour-promoting gain-of-functions similar to mutant p53.
During her PhD at the Medical University of Innsbruck, Lydia’s work was part of the EU-project PREDICTI-IV that aimed to improve the significance of in vitro models regarding the detection of adverse effects of pharmaceuticals using a combined omics-approach along with biokinetic quantification. She investigated the mechanistic effects of nephrotoxins on the functions of renal epithelial cells.